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RNA microarray was performed from lung adenocarcinoma cell CL1-0 and CL1-5 that were manipulated LCRMP-1 expression.

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308874
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Transcriptomic profiling of CL1-0 and CL1-5 cells with altered LCRMP-1 expression revealed that LCRMP-1 promotes angiogenesis by regulating angiogenesis facotr transcription, implicating its role as a transcriptional co-regulator in lung cancer progression. CL1-0 LCRMP-1 overexpressing cells (clone 1 and clone 2) were compared with CL1-0 Vector control cells. CL1-5 LCRMP-1 silencing cell was compared with CL1-5 Scramble control cell. Each experimental condition for all cell lines was performed with two biological replicates. Please note that each sample data was generated from both replicates.
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2025-10-02
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