Pre-Readout Evaluation Criteria — DT120-GAD Sealed Warrant (filed before topline)

Pre-readout evaluation criteria for the sealed warrant DT120-GAD-ADV-PROSPECTIVE-01. Filed and timestamped before any Phase 3 topline for Voyage (NCT06741228) or Panorama (NCT06809595) was public. This document fixes, while the outcome is still unknown, the rule by which the sealed assessment will later be judged a hit or a miss. It states what is not under test (the trial outcome), the specific falsifiable claims the seal recorded, the hit/partial/miss/inconclusive rule, confounders declared in advance, and a commitment to publish a miss with the same prominence as a hit. It accompanies the seal published 26 June 2026 (DOI 10.5281/zenodo.20943309) and its pre-readout self-audit (10.5281/zenodo.21365536) and independently authored control arm (10.5281/zenodo.21365394). This is a reasoning audit, not an outcome prediction. The trial outcome cannot validate or invalidate it.