Numbers and 30-month percentages1 of women with significant depression and anxiety, by randomisation arm, with odds ratios (OR) for initial colposcopy versus cytological surveillance, 95% confidence intervals (CI) and p-values (primary analysis).

1 Percentage over entire 30-month follow-up window, based on women's responses to questionnaires at 12, 18, 24 and 30 month time points.2 Significant depression defined as score of 8 or more on HADS depression subscale.3 Significant anxiety defined as score of 11 or more on HADS anxiety subscale.4 Odds ratio adjusted for minimisation variables: age-group, trial centre, high-risk HPV status and eligible cytology test status.5 Odds ratio adjusted for minimisation variables plus HADS anxiety at recruitment, HADS depression at recruitment, Carstairs' deprivation index, post-school education and training, physical activity, reproductive history, employment status, and MHLCS powerful others score.6 Odds ratio adjusted for minimisation variables plus HADS anxiety at recruitment, HADS depression at recruitment, smoking status, marital status and employment status.7 P-value from likelihood ratio test for dropping management arm from fully-adjusted model.