Analysis of cohesin-dependent gene regulation in fission yeast

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Analysis of cohesin-dependent gene regulation in fission yeast

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2010-08-12

Cohesin removal reprograms mitotic gene expression upon mitotic entry [ChIP-seq]. Cohesin removal reprograms mitotic gene expression upon mitotic entry [ChIP-seq]

During mitosis, the genome is restructured to facilitate chromosome segregation, accompanied by dramatic changes in gene expression. However, the mechanisms that underlie mitotic transcriptional regul

NIAID Data Ecosystem70

Cohesin residency determines chromatin loop patterns

The organization of chromatin into higher-order structures is essential for chromosome segregation, the repair of DNA damage, and the regulation of gene expression. These structures are formed by the

NIAID Data Ecosystem50

ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin-STAG1 from WAPL

The human genome folds to create thousands of loops connecting sites that are bound by the insulator protein CTCF and the ring-shaped cohesin complex. It is thought that most of these loops emerge thr

NIAID Data Ecosystem40

RAD21-TEV NLS-TEV RNAseq - extended cohesin depletion

RNA-seq of vehicle and doxycycline treated Rad21-TEV primary neuron transduced with NLS-TEV, inducing extended cohesin depletion Total of 6 samples analysed; 3 replicates of Rad21-tev primary neurons

NIAID Data Ecosystem60

Additional file 14: of A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe

Table S13. List of ChIP-seq samples. (XLSX 11 kb)

NIAID Data Ecosystem50