Endometrial cancer (EC) is the most frequent gynecological cancer. Tumor dissemination affecting ∼20% of EC patients is characterized at the primary carcinoma by epithelial-to-mesenchymal transition (
Complicating proteomic analysis of whole tissues is the obvious problem of cell heterogeneity in tissues, which often results in misleading or confusing molecular findings. Thus, the coupling of tissu
PTK2B is highly expressed in glioma DBTRG-05MG cells harboring BRAFV600E mutation, and its knockdown induces severe cell death. To explore the anti-tumor mechanism of targeting PTK2B and elucidate its