Summary of Adverse Events.

†Total adverse events encompasses all intensities. Mild = no interference with daily activities; moderate = interferes with daily activities; severe = daily activities interrupted. *Subjects with multiple symptoms were counted in all applicable symptom categories. ‡In skin surrounding the index lesion. Localized infections generally occurred at the biopsy site, although a causal relationship to the biopsy was not established. §One subject suffered from pre-existing anemia and cardiac arrhythmia. Mild, clinically insignificant elevations in serum creatinine were noted in both subjects at day 10 and resolved by day 20.