Characterization of the stromal vascular fraction (SVF) of human subcutaneous adipose tissue (SAT)

We report single-cell RNA-seq (Drop-seq) data from the stromal vascular fraction (SVF) of human subcutaneous adipose tissue (SAT). Potential subjects were recruited in a consecutive fashion, as scheduling permitted, from the plastic surgery operating room rosters at Beth Israel Deaconess Medical Center. Female subjects over the age of 18 undergoing elective plastic surgery procedures and free of other acute medical conditions were included and provided written informed consent preoperatively. Excess adipose tissue from the surgical site was collected at the discretion of the surgeon during the normal course of the procedure. Subjects with a diagnosis of diabetes, or taking insulin-sensitizing medications such as thiazolidinediones or metformin, chromatin-modifying enzymes such as valproic acid, anti-retroviral medications, or drugs known to induce insulin resistance such as mTOR inhibitors or systemic steroid medications, were excluded. >>> Submitter declares that the raw data will be deposited in dbGaP due to patient privacy concerns. <<<