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D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) H451 proof-reading deficient variant

NIAID Data Ecosystem2026-05-01 收录

DNA聚合酶校对机制

基因组稳定性研究

数据链接：

https://www.rcsb.org/structure/6HMF 数据链接链接失效反馈

官方服务：

资源简介：

D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) H451 proof-reading deficient variant

应用场景：

创建时间：

2024-01-24

基因组稳定性研究

染色体脆弱位点分析

Common fragile sites (CFSs) are regions susceptible to replication stress and are hotspots for chromosomal instability in cancer. Several features characterizing CFSs have been associated with their i

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Raw long read sequences of extrachromosomal circular DNA (eccDNA) from human and mouse cell lines

染色体外环状DNA

基因组稳定性研究

Long read sequences generated from extrachromosomal circular DNA (eccDNA) enrichment sample from human and mouse cell lines

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DRIP-sequencing U2OS

基因组稳定性研究

癌症治疗靶点

Here, we identify that a human DNA helicase RTEL1, which is known to play a role in the maintenance of telomeres by interacting with proteins in the shelterin complex by resolving G4 quadruplexes, is

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Effects of oxidative stress on mitotic recombination and genomic stability in yeast after 20 passages. Effects of oxidative stress on mitotic recombination and genomic stability in yeast after 20 passages

基因组稳定性研究

DNA损伤修复机制

Oxidative stress is a common factor threatening genomic stability in almost all aerobic organisms. Using a yeast screening system, we measured the frequency of mitotic recombination was greatly elevat

NIAID Data Ecosystem60

ERCC6L2 ensures repair fidelity at staggered-end DNA double-strand breaks

DNA损伤修复机制

基因组稳定性研究

Raw sequencing data for the study: "ERCC6L2 ensures repair fidelity at staggered-end DNA double-strand breaks"

NIAID Data Ecosystem20