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Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4u93
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Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990 Descriptor: (7R)-2-amino-7-[4-fluoro-2-(6-methoxypyridin-2-yl)phenyl]-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one, Heat shock protein HSP 90-alpha Authors: Bellamacina, C.R, Shafer, C.M, Bussiere, D. Deposit date: 2014-08-05 Release date: 2014-11-19 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Design, Structure-Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990. J.Med.Chem., 57, 2014
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2014-08-05
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