Figure_1.jpg

Variability in microbial composition among conditions (Fig.1a), and patients (Fig.1b) (R factoextra). The PCA plot Fig. 1.a separates samples according to caries status. The PCA plot Fig. 1.b separates samples according to subjects. Fig. 1a: Red represents biofilm samples from active non-cavitated caries lesions (CAa); green corresponds to arrested non-cavitated caries lesions (CAi), and blue to sound tooth surfaces (CAs). Fig. 1b: Red corresponds to all samples of CA1 patient (P1); olive green corresponds to all samples of CA2 patient (P2); green corresponds to all samples of CA3 patient (P3); blue corresponds to all samples of CA4 patient (P4), and purple corresponds to all samples of CA5 patient (P5). Ellipses represent 95% confidence interval.