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Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35

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Protein Data Bank Japan2025-06-18 更新2026-04-25 收录
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Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35 Descriptor: 4-[(3-ethanoylphenyl)sulfamoyl]-~{N}-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]benzamide, D-3-phosphoglycerate dehydrogenase Authors: Cen, Y, Gao, D, Zhou, J, Tian, P. Deposit date: 2021-08-27 Release date: 2023-03-08 Last modified: 2025-06-18 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy. J.Med.Chem., 66, 2023

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2021-08-27
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