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Spo11-oligo mapping of double-strand breaks in pch2 and sir2 mutants

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NIAID Data Ecosystem2026-03-11 收录
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The Spo11-generated double-strand breaks (DSBs) that initiate meiotic recombination are non-randomly distributed across the genome. Here, we use Spo11-oligonucleotide complexes, a byproduct of DSB formation, to map the distribution of meiotic DSBs in pch2 and sir2 mutant strains of Saccharomyces cerevisiae. Two samples from each strain (four total) collected at 4 hr after transfer to sporulation medium

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2019-03-12
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