CKF in a Haitian hospital data.xlsx

This is data from the Nephrology Department of the State
University Hospital of Haiti (HUEH). The study population included all patients
diagnosed with CKF at HUEH or elsewhere, who are followed in the Nephrology
Department from January 2015 to September 2019. The study population was
selected according to these criteria:

Inclusion criteria

-Patients diagnosed with CKF at HUEH or elsewhere and who
are monitored in the dialysis unit during the study period.

-Patients with CKF diagnostic laboratory tests in their
file, including at least: a high creatinemia and/or a high blood urea level
and/or an ultrasound with abnormalities, and/or a renal biopsy with fibrosis.

Exclusion criteria

-Patients with incomplete medical records i.e., not
including age, sex, reasons for consultation, and clinical signs
simultaneously.

An individual collection sheet was prepared in Epi Info
7. All the data collected was well saved without any personal information that
could reveal the patients' identity.

We defined the year of admission as the year of the
patient's first consultation in the department during the study period. Age is
noted as mentioned in the file, measured in completed years (exact age), and
then categorized ​​(age groups). Sex is determined on the male and female dichotomous
scale. The provenance is measured according to the department where the person
resides among the 10 in the country. Occupation is defined as the regular
activity conducted by the patient to earn a living. Those activities can be
regarded as professions such as trader, teacher, nurse, engineer, mason, and
plumber...These socio-demographic data are taken from the first record recorded
for the patient.

The reasons for consultation, clinical signs, history,
and associated pathologies are noted as mentioned in the first consultation
form. The etiology of CKF is known from the diagnosis. We determined the stage
of the CKF of each patient from the glomerular filtration rate which is
calculated thanks to the application of Medscape from the serum creatinine
level according to the MDRD equation: Moderate stage (30-59ml / min /1.73m²);
Severe stage (15-29 ml/min / 1.73m²); Terminal stage (Creatinine clearance
<15ml / min / 1.73m²).

For the data of the paraclinical examinations, we
considered the results of the first examinations reported by the patients after
the first consultation. The dosage of creatinemia, the normal value of which is
between 0.9 and 1.3 mg/dl. The hemoglobin level was used to diagnose anemia if
it was less than 12 g/dl in women and less than or equal to 13 g/dl in men. We
speak of severe anemia when the hemoglobin level is less than 8g/dl. The dosage
of urea nitrogen with a normal value between 7 and 20 mg/dl. Calcemia with a
normal value of 8.7 to 10.4 mg/dl. There is hypocalcemia below 8.7 mg/dl and
hypercalcemia above 10.4 mg/dl. Phosphoremia with a normal value: 2.5-4.8
mg/dl. There is hypophosphatemia below 2.5 mg/dl and hyperphosphatemia above
4.8 mg/dl. The data from the renal ultrasound are taken from the conclusions of
the operator who performed it on the size, echostructure of the kidneys, and
cortico-medullary differentiation. Examination of urine for the presence of
leukocyturia, hematuria, proteinuria.

For complications, we noted all the information from the
patient follow-up sheets. The data on the prescribed treatment is taken from
the follow-up sheet closest to the first consultation: antihypertensive agent
to control high blood pressure is measured according to the number of drugs
prescribed and the antihypertensive drugs class: ACE inhibitors, diuretics,
calcium channel blockers, ARBs, Vasodilators, Beta-blockers; Antianemic
treatment to correct anemia is measured according to 3 modalities (iron, blood
transfusion, EPO). The outcome of patients is measured according to 4 methods
(Abandonment, followed elsewhere, deceased, dialysis). We noted information
directly on the coverage of files as for cases of abandonment, death, and
followed elsewhere, we noted the patients who are still on hemodialysis during
blood collection using the list available at the Nephrology Department.

The data are entered in Excel and processed by Epi Info 7
and SPSS software 20. Qualitative variables are measured by frequency and
percentage calculations and quantitative variables by measures of central tendency
(mean, median) and quartiles for some. As the distribution of our data was not
normal, we used the nonparametric Kruskal-Wallis test to compare the mean of
age as a function of the etiology and the means of serum creatinine level and
urea nitrogen level as a function of the stage of CKF then as a function of the
etiology having more than two modalities with p-value <0.05 as the
significance level. Fisher's exact test was used for qualitative variables:
urine analysis (leukocyturia) and stage of CKF, etiology of CKF and associated
history and pathologies (hypertension and diabetes), etiology of CKF, and
gender.