首页/数据集/Alteration in global transcriptome after Notch inhibition with gamma-secretase inhibitor MRK003 in Glioblastoma Cells

Alteration in global transcriptome after Notch inhibition with gamma-secretase inhibitor MRK003 in Glioblastoma Cells

ChEBI2015-08-07 更新2026-07-12 收录

胶质母细胞瘤分子机制

转录组药物响应

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-71769 数据链接链接失效反馈

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资源简介：

Alteration in global transcriptome after Notch inhibition with gamma-secretase inhibitor MRK003 in Glioblastoma Cells

应用场景：

创建时间：

2015-08-07

胶质母细胞瘤分子机制

增强子分析

Here, by mapping H3K27ac deposition, we analyze the active regulatory landscapes across primary GBM biopsies, normal brain tissues, and cell line counterparts. Analysis of differentially regulated enh

NIAID Data Ecosystem90

Effect of Regnase-2/MCPIP2/ZC3H12B overexpression in human glioblastoma U-251 MG cell line.

胶质母细胞瘤分子机制

差异表达转录组分析

Regnase-2/MCPIP2/ZC3H12B is a protein belonging to the ZC3H12 protein family. There are three other proteins of this family present in humans of which Regnase-1/MCPIP1/ZC3H12A is the founder member as

NIAID Data Ecosystem20

Expression data from kidney tissues treated with vehicle, losartan and metformin. Expression data from kidney tissues treated with vehicle, losartan and metformin

肝肾疾病药物机制

转录组药物响应

Chronic kidney disease (CKD) is one of the major global health problems with high incidence, poor prognosis and high medical cost. However, few pharmacological options are available for CKD. Metformin

NIAID Data Ecosystem20

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]. Homo sapiens

肿瘤耐药机制

转录组药物响应

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

NIAID Data Ecosystem50

MiR-328 expression values showed negative correlation to KIF23 protein expression levels in 60 pGBM samples.

胶质母细胞瘤分子机制

miRNA-蛋白质关联分析

MiR-328 expression values showed negative correlation to KIF23 protein expression levels in 60 pGBM samples.

Figshare2015-12-02 更新20