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Kinetic analysis for oxidations of typical human CYP2C9 substrates catalyzed by monkey CYP2C93.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Kinetic_analysis_for_oxidations_of_typical_human_CYP2C9_substrates_catalyzed_by_monkey_CYP2C93_/470510
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Each substrate (0–5000 µM tolbutamide, 0–200 µM diclofenac, and 0–200 µM flurbiprofen) was incubated with recombinant CYP2C93v1 (of rhesus monkey) at 37°C for 15 min in the presence of an NADPH-generating system as described in Materials and Methods. Kinetic parameters were calculated from a fitted curve by non-linear regression (mean ± SE).
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2015-12-02
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