Spo11-oligo mapping in zip3 mutants

Meiotic recombination promotes genetic diversification as well as pairing and segregation of homologous chromosomes, but the double-strand breaks (DSBs) that initiate recombination are dangerous lesions that can cause mutation or meiotic failure减数分裂重组（Meiotic recombination）不仅能够促进遗传多样化，还可介导同源染色体（homologous chromosomes）的配对与分离；但启动重组过程的双链断裂（double-strand breaks, DSBs）属于危险的DNA损伤事件，可能引发突变或减数分裂失败（meiotic failure）。