SARS coronavirus and innate immunity

SARS-CoV triggers the hosts innate immune system via the type I interferon system in dendritic cells and macrophages, which activate ISRE and IFN-b sentitive promoter elements.SARS-CoV 通过树突状细胞和巨噬细胞中的I型干扰素系统触发宿主的先天免疫系统，该系统激活ISRE和IFN-b敏感的启动子元件。