遇见数据集

Evidence for toxic CAG trinucleotide repeats contributing to Huntington's disease though RNA interference

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NIAID Data Ecosystem2026-05-01 收录
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Mutant huntingtin CAG trinucleotide repeat mimetic hairpins are loaded into the RISC and kill cells through RNAi Overall design: NB7 cells were transfected with different HP mimicking two different mHTT variants or CAG control siRNAs. Subsequently, Ago protein associated short RNAs were pulled down using a GW182 peptide and subjected to smRNA Seq

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2023-06-30
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