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Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline

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Protein Data Bank Japan2025-05-28 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8fx5
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Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline Descriptor: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Vuckovic, Z, Mobbs, J.I, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. Deposit date: 2023-01-23 Release date: 2023-09-13 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (2.45 Å) Cite: Xanomeline displays concomitant orthosteric and allosteric binding modes at the M 4 mAChR. Nat Commun, 14, 2023
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2023-01-23
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