Effect of the E1-A226V mutation on infectivity of different strains of CHIKV to <i>Ae. albopictus</i> mosquitoes.

Exp – experiment number. E1-226 – amino acid at position E1-226. N m – number of mosquitoes used to estimate OID50 value. OID50 (C95) – oral infectious dose 50 and 95% confidence intervals are expressed as Log10TCID50/ml. OID50 values and confidence intervals were calculated using PriProbit (Version 1.63). p – comparison of statistical significance of difference in OID50 values between viruses with E1-226A and E1-226V mutations. Comb – combined summary of two independent experiments published earlier [9]. NG – value is not given.