Regulation effect and mechanism of Sheng-Hua-Tang on female reproductive system: from experimental transcriptomic analysis to clinical applications. Regulation effect and mechanism of Sheng-Hua-Tang on female reproductive system: from experimental transcriptomic analysis to clinical applications

Sheng-Hua-Tang (SHT) is commonly used to treat female illnesses, especially postpartum conditioning. However, its effects and mechanisms on female reproductive system remain unclear. The aim of the present study was to investigate the effect of SHT on female brain-ovary-uterus axis from bench to clinic. Overall design: Mice were administrated SHT (200 mg/kg) orally for seven consecutive days. Brain, ovary, and uterus tissues were then collected for microarray analysis.