The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide modification
收藏Protein Data Bank Japan2024-02-07 更新2026-03-28 收录
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The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide modification Descriptor: DNA (5'-D(*CP*TP*(05H)P*TP*CP*TP*TP*TP*G)-3'), POTASSIUM ION, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') Authors: Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. Deposit date: 2021-06-29 Release date: 2022-08-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
创建时间:
2021-06-29



