Light-Driven Carbon–Carbon Coupling of α‑sp3–CH of Aliphatic Alcohols with sp2–CH Bond of 1,4-Naphthoquinones

Here, an α-selective Csp3–H bond functionalization of primary aliphatic alcohols with 1,4-naphthoquinones yielded Csp2–Csp2 coupled products driven by blue-LED light under catalyst, metal, base, and reagent-free conditions. In this transformation, cleavage of three C–H bonds (two sp3–C-H, one sp2–C–H, and one O–H) and four new bonds formed, leading to fluorescent 2-acylated-1,4-naphthohydroquinones.