Effect of intramyocardial WDR12 gene delivery on cardiac structure and function in normal adult rat hearts, post-infarction, and in angiotensin II-induced hypertension at 1 week.

MI, myocardial infarction; Ang II, angiotensin II; LV, left ventricular; IVRT, isovolumic relaxation time
Adenoviral gene construct expressing WDR12 and LacZ were injected into LV free wall and echocardiographic measurements were performed at 1 week after gene transfer. The results are expressed as mean±SEM (n = 7–10).
*P<0.05,
**P<0.01 vs LacZ (Student t test).
Effect of intramyocardial WDR12 gene delivery on cardiac structure and function in normal adult rat hearts, post-infarction, and in angiotensin II-induced hypertension at 1 week.