Effect of intramyocardial WDR12 gene delivery on cardiac structure and function in normal adult rat hearts, post-infarction, and in angiotensin II-induced hypertension at 1 week.

MI, myocardial infarction; Ang II, angiotensin II; LV, left ventricular; IVRT, isovolumic relaxation time Adenoviral gene construct expressing WDR12 and LacZ were injected into LV free wall and echocardiographic measurements were performed at 1 week after gene transfer. The results are expressed as mean±SEM (n = 7–10). *P<0.05, **P<0.01 vs LacZ (Student t test). Effect of intramyocardial WDR12 gene delivery on cardiac structure and function in normal adult rat hearts, post-infarction, and in angiotensin II-induced hypertension at 1 week.