The clinical impact of bacterial co-infection among moderate, severe and critically ill COVID-19 patients in the second referral hospital in Surabaya

Background

Data on the prevalence of bacterial co-infections among COVID-19 patients are limited, especially in our country. We aimed to assess the rate of bacterial co-infections in hospitalized COVID-19 and report the most common microorganisms involved and the antibiotic use in these patients.

Methods

This study is a cross sectional study with retrospective approach, among COVID-19 adult patients admitted to Universitas Airlangga Hospital Surabaya from 14 March-30 September 2020. The bacterial infection is defined based on clinical assessment, laboratory parameters, and microbiology results.

Results

Total of 218 patients with moderate to critical ill and confirmed COVID-19 were included in this study. Bacterial infection was confirmed in 43 patients (19.7%). COVID-19 patients with bacterial infections had longer hospital length of stay (17.6 ± 6.62 vs 13.31±7.12), a higher proportion of respiratory failure, ICU treatment, and ventilator use. COVID-19 patients with bact...