Cytochrome c folding pathway: Kinetic native-state hydrogen exchange
收藏PubMed Central2002-08-26 更新2026-05-16 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC129417/
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资源简介：
Native-state hydrogen exchange experiments under EX1 conditions can distinguish partially unfolded intermediates by their formation rates and identify the amide hydrogens exposed and protected in each. Results obtained define a cytochrome c intermediate seen only poorly before and place it early on the major unfolding pathway. Four distinct unfolding steps are found to be kinetically ordered in the same pathway sequence inferred before.
提供机构：
National Academy of Sciences
创建时间：
2002-08-26
