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BindingDB Entry 7628: Thienopyrimidinone derivatives as mGluR1 antagonists

Name: BindingDB Entry 7628: Thienopyrimidinone derivatives as mGluR1 antagonists
Creator: BindingDB
Published: 2018-11-07T01:32:43+08:00

DataCite Commons2026-03-21 更新2026-05-06 收录

药物靶点相互作用

神经病理性疼痛药物发现

数据链接：

https://ezid.cdlib.org/tombstone/id/doi:10.7270/Q2H9941W 数据链接链接失效反馈

官方服务：

资源简介：

Small molecule binding data for protein Metabotropic glutamate receptor 1, Uniprot Q13255

应用场景：

提供机构：

BindingDB

创建时间：

2018-11-07

肿瘤药物靶点验证

抑制剂筛选

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BindingDB Entry 50018636: Overview of piperlongumine analogues and their therapeutic potential.

配体-蛋白质相互作用

药物靶点筛选

Small molecule binding data for protein Aldo-keto reductase family 1 member B1, Uniprot P15121

DataCite Commons2024-04-26 更新70

ALK in complex with NVL-655 with in-silico mutated residue

药物靶点相互作用

抗性分析

PyMol session file (.pse) files of the structure of ALK in complex with NVL-655 (original PDB accession 9GBE) with in-silico mutated residues as reported in figure 4. Computational mutagenesis

Figshare2025-01-22 更新40

BindingDB Entry 50018236: Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1.

药物发现

蛋白质结合

Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Lysine-specific histone demethylase 1A, and REST corepressor 1, Uniprot O60341, P21397

DataCite Commons2024-04-26 更新70

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain

神经病理性疼痛药物发现

Trk受体

Hormones of the neurotrophin family, nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT3), and neurotrophin 4 (NT4), are known to activate the family of Tropomyosi

Figshare2018-07-27 更新70

BindingDB Entry 7628: Thienopyrimidinone derivatives as mGluR1 antagonists

资源简介：

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