Multi-gesture drag-and-drop decoding in a 2D iBCI control task

Objective. Intracortical brain-computer interfaces (iBCIs) have demonstrated the ability to enable point-and-click as well as reach-and-grasp control for people with tetraplegia. However, few studies have investigated iBCIs during long-duration discrete movements that would enable common computer interactions such as ”click-and-hold” or ”drag-and-drop.”
Approach. Here, we examined the performance of multi-class and binary (attempt/no-attempt) classification of neural activity in the left precentral gyrus of two BrainGate2 clinical trial participants performing hand gestures for 1, 2, and 4 seconds in duration. We then designed a novel ”latch decoder” that utilizes parallel multi-class and binary decoding processes and evaluated its performance on data from isolated sustained gesture attempts and a multi-gesture drag-and-drop task.
Main Results. Neural activity during sustained gestures revealed a marked decrease in the discriminability of hand gestures sustained beyond 1 second. Compare..., , , # Multi-gesture drag-and-drop decoding in a 2D iBCI control task

These data are released with the manuscript - Gusman, Hosman, et al, 2025, [Multi-gesture drag-and-drop decoding in a 2D iBCI control task.](https://iopscience.iop.org/article/10.1088/1741-2552/adb180)

Dataset DOI: [10.5061/dryad.98sf7m0v1](https://doi.org/10.5061/dryad.98sf7m0v1)

**Dataset Description**

This dataset comprises intracortical neural signals recorded from two participants enrolled in the BrainGate2 pilot clinical trial (NCT00912041):

* **T11:** A 39-year-old man with tetraplegia due to a C4 AIS-B SCI that occurred 9 to 11 years prior to enrollment in the trial.
* **T5:** a 70-year-old man with tetraplegia due to a C4 AIS-C spinal cord injury that occurred 9 to 11 years prior to enrollment in the trial.

This research was conducted under an Investigational Device Exemption (IDE) granted by the US Food and Drug Administration (IDE #G090003; CAUTION: Investigational device. Limited by Federal law to investi..., We confirm that the informed consent form signed by participants permits sharing of coded data that does not contain other identifying information. Neural data contain no personally identifiable information (PII). Filenames only have a code, but no PII.