5Aza and TSA treatment of MCF7 cells (BS-seq). 5Aza and TSA treatment of MCF7 cells (BS-seq)
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJEB10087
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资源简介：
The goal of this study is to identify the DNA methylation changes caused by exposure of to the DNMT inhibitor 5-aza-2â-deoxycytidine (5Aza) and HDAC inhibitor Trichostatin A (TSA). We performed whole-genome bisulfite sequencing of the drug-treated MCF7 breast cancer cell lines and compare their DNA methylation profile with the untreated MCF7 (see E-MTAB-2014). While MCF7 treated with both drugs experienced global loss of DNA methylation, the 5Aza induced stronger demethylation than TSA.
创建时间：
2016-07-01
