RNA-seq of heart from adult mice 4 and 48 hours post MycER activation compared controls

Aim: To determine RNA expression levels in heart tissues of mice 4 and 48 hours post Myc activation. Mice were systemically infected with a cardiomyocyte specific adeno associated virus (AAV9) at 4 to 6 weeks of age. Hearts were isolated from adult mice that had been infected with AAV9-Ccnt1 and were either Myh6-cre;R26CAG-c-MycERT2/+ or R26CAG-c-MycERT2/+ following 4 hours of MycER activation via administration of (Z)-4-hydroxytamoxifen. Hearts were isolated from adult mice that had been infected with either AAV9-Ccnt1 or AAV9-RFP and were R26CAG-c-MycERT2/+ 48 hours post a single injection of tamoxifen to induce MycER activity.