Copper-Catalyzed Direct C-5 Fluorination of 8-Aminoquinolines by Remote C–H Activation
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0037-1610130
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资源简介:
A convenient method was developed for direct regioselective fluorination of 8-aminoquinolines at the C-5 position by copper-catalyzed remote C–H activation using Selectfluor as the electrophile fluorinating reagent. With this method, diverse fluorinated quinoline derivatives were facilely obtained under mild conditions with moderate yields.
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© Georg Thieme Verlag
创建时间:
2017-02-28



