File S1 - Impact of Acetazolamide and CPAP on Cortical Activity in Obstructive Sleep Apnea Patients

Table S1. Sleep and respiratory variables in study 1 [1]. OSAS patients withdrawn from CPAP treatment. *p<0.05, compared to 490 m (Wilcoxon signed ranks test). ‡p<0.05, compared to corresponding placebo condition at the same altitude (Wilcoxon signed ranks test). Data are shown as medians and interquartile ranges. AHI: Apnea/Hypopnea Index; SpO2: Oxygen saturation; etCO2: End tidal carbon dioxide pressure; REMS: Rapid-eye movement sleep; SWS: Slow-wave sleep; TST: Total sleep time; TIB: Time in bed; Sleep efficiency. TST as percentage of TIB. N = 39. Table S2. Sleep and respiratory variables in study 2 [2]. OSAS patients treated with CPAP. *p<0.05, compared to 490 m with CPAP (Wilcoxon signed ranks). ‡p<0.05, compared to corresponding placebo condition at the same altitude (Wilcoxon signed ranks). Data are shown as medians and interquartile ranges. AHI: Apnea/Hypopnea Index; SpO2: Oxygen saturation; PtcCO2: Transcutaneous carbon dioxide pressure; REMS: Rapid-eye movement sleep; SWS: Slow-wave sleep; TST: Total sleep time; TIB: Time in bed; Sleep efficiency. TST as percentage of TIB. N = 41. Discussion S1. Supporting discussion. References S1. Supporting references.
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