Multicomponent One-Pot Procedure for the Synthesis of Free α-Chiral Amines from Aldehydes
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https://figshare.com/articles/dataset/Multicomponent_One_Pot_Procedure_for_the_Synthesis_of_Free_Chiral_Amines_from_Aldehydes/3250405
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资源简介：
The synthesis of free α-chiral amines by a one-pot multicomponent procedure from commercially available starting
materials is described. This enantioselective reaction involves a catalytic asymmetric addition of dialkylzinc reagents to N-diphenylphosphinoylimines with use of an air-stable precatalyst complex 1. The α-chiral amines are
prepared with a one-pot procedure from alkyl and aryl
aldehydes in good yield (41−90%) and with excellent enantioselectivity (90−97% ee).
创建时间：
2016-05-05
