Hippocampal Neuroanatomical Measurements between Disc131L/31L, Disc1100P/100P and wild-type mice.

A significant difference only in dentate granule cell layer thickness between wild-type and Disc1100P/100P mice was noted (ANOVA F(2,20) = 4.07, P = 0.032; post-hoc Bonferroni pt test indicated a strong correlation (p = 0.06) between wild-type and Disc131L/31L mice. Within the hippocampus, the thinning of the granule cell layer in the mutants is specific to the dentate gyrus, as no significant differences are observed between genotypes in the thickness of the pyramidal cell layer in the CA1 and CA3 regions, and the overall height and width of the hippocampus. Data presented as mean ± SEM.Hippocampal Neuroanatomical Measurements between Disc131L/31L, Disc1100P/100P and wild-type mice.