five

Human dUTPase in complex with novel uracil derivative

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Human dUTPase in complex with novel uracil derivative Descriptor: Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, N-{5-[(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy]-2-methylpentan-2-yl}benzenesulfonamide Authors: Chong, K.T, Miyahara, S, Miyakoshi, H, Fukuoka, M. Deposit date: 2010-12-03 Release date: 2010-12-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors J.Med.Chem., 55, 2012
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2010-12-03
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