Summary of mRNA induction, protein induction and translation efficiency for each Fluc reporter construct.

Results presented in Figure 4 were compiled and for each construct, the relative translation efficiency was calculated as the ratio of the average firefly luciferase activity induction (normalized to siGFP, untreated cells set as 1) over to the average firefly luciferase mRNA induction (normalized to siGFP, untreated cells set as 1). The fold difference between siGFP + IFN and siG12C +IFN is shown in bold in the fourth column. The p-values for the differences in mRNA and Fluc induction between siGFP + IFN-β and siG12C + IFN-β conditions are indicated: ns, non significant;* p** p***p