Enantioselective Preparation of P-Chiral Phosphine Oxides
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https://figshare.com/articles/dataset/Enantioselective_Preparation_of_i_P_i_Chiral_Phosphine_Oxides/2570947
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A highly efficient chiral auxiliary-based strategy for the asymmetric synthesis of P-chiral phosphine oxides in >98:2 er has been developed. The methodology involves the highly stereoselective formation of P-chiral oxazolidinones that then undergo displacement with a variety of Grignard reagents to prepare the desired phosphine oxides.
创建时间:
2016-02-22



