The ubiquitin ligase TRIM37 controls cancer-specific vulnerability to PLK4 inhibition
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148263
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资源简介：
We show synthetic lethality between PLK4 inhibition-mediated centrosome loss and the overexpression of the ubiquitin ligase TRIM37 in cancer cells with amplification of Chr17q Compare the effect of differential TRIM37 expression on global gene expression in untransformed hTERT RPE1 and neuroblastoma CHP-134 cells.
创建时间：
2020-09-18
