Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development that informs Chemically Reactive Metabolite formation

Transcriptional responses in rat liver following treatment with compounds with a range of in vitro covalent binding measurements经一系列具有不同体外共价结合测定值的化合物处理后，大鼠肝脏中的转录响应