Budding yeast RNA polymerase II CTD phosphorylation and transcription termination factor localization

Whole genome analysis of total RNA pol II, Ser2-, Ser5- and Ser7-phosphorylated RNA pol II, in WT and mutants of the C-terminal domain (CTD) kinases Ctk1 and Kin28, and localization of the termination factors Pcf11, Nrd1 and Rat1.针对野生型（Wild Type, WT）及羧基末端结构域（C-terminal domain, CTD）激酶Ctk1与Kin28的突变株，开展总RNA聚合酶II（RNA polymerase II, RNA pol II）、丝氨酸2位、丝氨酸5位及丝氨酸7位磷酸化RNA聚合酶II的全基因组分析，并完成终止因子Pcf11、Nrd1与Rat1的定位研究。