LARP7
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1604813
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资源简介:
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
该基因编码一种蛋白质,该蛋白质存在于7SK小核糖核蛋白(small nuclear ribonucleoprotein)中。此snRNP复合物抑制了周期依赖性激酶(cyclin-dependent kinase)、正转录延伸因子b(positive transcription elongation factor b),该因子对于在启动子处使暂停的RNA聚合酶II(RNA polymerase II)开始转录延伸是必需的。该基因的一个伪基因位于第3号染色体上。选择性剪接导致多种转录变体。 [由RefSeq提供,2012年5月]
提供机构:
Rat Genome Database



