Activity of NOD2 selective compounds and inhibitors of IKK and RIP2 in cell-based assays used for hit identification and triage.
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IC50 values are given in micromolar, as the mean and standard deviation. In each of the cell-based assays the end-point measured was IL-8. In the RIPK2 biochemical assay autophosphorylation of RIPK2 was determined.
创建时间:
2013-08-01



