Hepatic mRNA expression of inflammatory mediators 6 h after intravenous injection of PfHz.

Median values are shown for each group (n = 3–12) and min-max values are indicated between parentheses. Data were stratified according to the amount of PfHz in the liver (Li): 200 nmol PfHz; Statistically different from PBS administered mice:* p** p*** pStatistically different from PfHz Li †p††pFasL, Fas ligand; Hmox1, heme oxygenase 1; ICAM-1, intercellular adhesion molecule-1; IFN-γ, interferon-gamma; IL-, interleukin-; iNOS, inducible nitric oxide synthase; IP-10, interferon gamma inducible protein-10; KC, keratinocyte-derived chemokine; LT-α, lymphotoxin-alpha; MCP-1, monocyte chemotactic protein-1; MHC-II, major histocompatibility complex class II; MMP-9, matrix metalloproteinase-9/gelatinase B; NOX2, NADPH oxidase 2; TGF-β, transforming growth factor-beta; TNF, tumor necrosis factor.Hepatic mRNA expression of inflammatory mediators 6 h after intravenous injection of PfHz.