Information of the 26 lung function-associated SNPs selected in the present study [13], [14], [15], [16].

Columns 1 to 9 refer to frequencies, beta and p values for the association of SNPs with lung function fenotypes as found in the literature. Columns 10 to 15 refer to the frequencies and total sample sizes of the same or proxy-SNPs that were looked up in IMPROVE.SNP ID: rs number for the SNPs selected from literature. Chr: chromosome, A1: coded allele, A1 freq: frequency of the coded allele, Measure reported: phenotype for which the SNP reached genome-wide significant association, SE: standard error, P: p-value for association with measure reported, proxy LD: linkage disequilibrium between SNP ID from literature (column 1) and the proxy used for replication in IMPROVE (column 11), proxy SNP: rs number for the proxy SNPs used for replication in IMPROVE, n: number of individuals tested in IMPROVE.