Mitochondrial complex I regenerates NAD+ and proton pumps for TCA cycle function and ATP production, respectively. Mitochondrial complex I dysfunction has been implicated in many brain pathologies inc
The GCG repeated sequence (bold) begins 73 bp upstream of the initiator Met. There are 7 repeats in this region of the APP gene in BALB/c mice as compared to 4 in C57BL/6.
