数据链接：
官方服务：
资源简介：
pERK score in Spred2 immunostaining pattern.
应用场景：
创建时间：
2021-11-24
相关数据集
Table_1_WDPCP Modulates Cilia Beating Through the MAPK/ERK Pathway in Chronic Rhinosinusitis With Nasal Polyps.DOCX
Cilia loss and dysfunction is one of the typical pathological features of chronic rhinosinusitis with nasal polyps (CRSwNP). Tryptophan-aspartic acid (W-D) repeat containing planar cell polarity effec
NIAID Data Ecosystem450
MAPK/ERK activation determines a distinct transcriptional program following neuronal activity in the murine hippocampus. Mus musculus
Kanate was used to induce seizures in mice, and gene expression in the hippocampus was measured Using MEK inhibitors, MEK-dependent gene expression was assessed. Overall design: Untreated controls wer
NIAID Data Ecosystem90
Additional file 3 of Assessment of the FRET-based Teen sensor to monitor ERK activation changes preceding morphological defects in a RASopathy zebrafish model and phenotypic rescue by MEK inhibitor
Supplementary Material 2
DataCite Commons2024-08-15 更新70
ITGB1 promotes the chondrogenic differentiation of human adipose-derived mesenchymal stem cells by activating the ERK signaling
In current study, we found that ITGB1 gene overexpression significantly elevated COL II (collagen II), aggrecan and SOX9 (SRY-Box 9) expression but suppressed COL I (collagen I) expression in hADSCs.
NIAID Data Ecosystem100
Withdrawal of MEK1/2 inhibitor reverses acquired resistance driven by BRAF amplification but drives EMT and chemoresistance in cells with amplified KRAS
Acquired resistance to MEK1/2 inhibitors can arise through amplification of BRAFV600E or KRASG13D to reinstate ERK1/2 signalling. Here we show that BRAFV600E amplification and selumetinib resistance a
NIAID Data Ecosystem80
