five

Crystal structure of human PLU-1 (JARID1B) in complex with KDOAM25a

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Protein Data Bank Japan2026-03-04 更新2026-03-21 收录
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Crystal structure of human PLU-1 (JARID1B) in complex with KDOAM25a Descriptor: 1,2-ETHANEDIOL, 2-[[[2-[2-(dimethylamino)ethyl-ethyl-amino]-2-oxidanylidene-ethyl]amino]methyl]pyridine-4-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Srikannathasan, V, Johansson, C, Gileadi, C, Nuzzi, A, Ruda, G.F, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Brennan, P, Oppermann, U. Deposit date: 2015-06-02 Release date: 2015-07-08 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol, 24, 2017
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2015-06-02
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