PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors
收藏NIAID Data Ecosystem2026-05-10 收录
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资源简介：
MD-224 is a PROTAC that induces degradation of the human protein MDM2. However, we have found that it also induces degradation of a subset of nuclear receptors. DIA was performed to assess the overall specificity of MD-224 in 293T cells and the colorectal cancer cell line SNU-C4.
创建时间：
2025-09-18
