Ruthenium Complexes as Protein Kinase Inhibitors
收藏NIAID Data Ecosystem2026-03-06 收录
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Replacing complex natural products with simple metal complexes could lead to a new class of metallopharmaceuticals in which the metal center plays mainly a structural role. A strategy is introduced for the creation of ruthenium complex-based protein kinase inhibitors 1 (X = CO or CH2), morphed out of the class of indolocarbazole inhibitors with the alkaloid staurosporine as its most prominent member.
创建时间：
2004-02-19
